what affects the overall rate of the reaction? Vmax or Km? would a lower Km result in a faster react… Show more what affects the overall rate of the reaction? Vmax or Km? would a lower Km result in a faster reaction rate? or would a higher Vmax result in a faster reaction? I know that rate depends on rate constant and concentration of the substrate but I am wondering want are the effects on reaction kinetics with positive and negative effectors. • Show less